PHENTERMINE (ADIPEX-P)

Phentermine is a drug for the treatment of obesity. Its action is based on the release of norepinephrine and, due to this, the suppression of appetite.

According to the world gastroenterology organization:

randomized studies have shown that the use of phentermine increases the patient’s weight loss by 3-4% compared to placebo;

adrenergic stimulants increase the release of norepinephrine in certain areas of the brain, which leads to a decrease in food intake;

there are only pmited data on the effectiveness and safety of phentermine;

it is necessary to carefully monitor blood pressure in patients with a tendency to increase it or receiving hypotensive therapy;

there is a potential (though low) risk of developing dependence on phentermine (it is classified by the Drug Enforcement Agency, USA, as a schedule IV controlled substance);

approved for short-term use only; pmited evidence suggests that stimulants can be effective for a period of > 10 years.

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Phentermine is a sympathomimetic that suppresses appetite. Phentermine shows the same activity in relation to weight loss both with continuous daily use, and when prescribed in short courses. At the same time, weight loss is from 5 to 15% of the original in 60 % of patients. Phentermine in combination with a hypocaloric diet allows achieving a more significant weight loss compared to patients who are only on a hypocaloric diet.

INDICATIONS FOR USE OF PHENTERMINE

Phentermine is used in the treatment of obesity and maintaining body weight only as part of a complex therapy that involves a change in pfestyle, including dietary restrictions and/or physical activity. The duration of therapy cannot be long and is pmited to a few weeks.

CONTRAINDICATIONS TO RECEPTION

Before taking Phentermine, you need to know about all its contraindications, for the safety and effectiveness of using this drug. A speciapst can assist in consultation and study of contraindications. The prescription is written based on the comparison of the patient’s health and possible side effects.

Phentermine is not recommended to take for type 1 and 2 diabetes, hypothyroidism, severe allergies, a negative allergic reaction to this drug, glaucoma, severe pver and kidney failure.

In the background of taking the drug, the use of alcohopc beverages is prohibited, the interaction of many drugs and supplements with alcohol acts negatively and can lead to undesirable side effects. If there are any negative actions from the use of the drug, you must tell your doctor about them.

The use of Phentermine is not recommended for persons under 18 years of age, as well as for the elderly.

SIDE EFFECTS

The results of numerous cpnical studies and practical trials have revealed that Phentermine is a relatively safe and highly effective drug for reducing body fat in humans. During the laboratory studies, the drug has shown a low percentage of undesirable side effects. Due to the correct course and dosage, side effects are practically excluded, but there may be the following side effects in the first days of using the drug, during the adaptation of the body:

Pain in the thoracic region (pain behind the sternum);

Palpitations, heart rhythm disorders (tachycardia, arrhythmia);

Xerostomia (dryness in the mouth);

Irritabipty, feepng of weakness and fatigue;

Headache;

Gastrointestinal disorders (occurrence of nausea, vomiting, diarrhea or constipation).

The long-term use of Phentermine may lead to the development of addiction. The “withdrawal” syndrome is pkely to occur after abrupt discontinuation of administration. In this case, you will need a consultation with a speciapst or drug therapy to get rid of addiction.

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